The administration of U.S. President Donald Trump has officially launched Genesis Mission, a nationwide initiative designed to accelerate scientific breakthroughs and technological development through advanced artificial intelligence.
The executive order was signed at the White House on November 24, 2025.
The document frames the program as a response to an intensifying global tech race where AI capability has become a defining factor of national power. Trump emphasized that the scale of the challenge requires unprecedented national mobilization:
“The challenges we face demand a historic, all-of-nation effort — one matching the urgency and ambition of the Manhattan Project.”
What Genesis Mission Will Do
At the heart of the initiative is the creation of a unified, integrated AI platform that merges federal scientific data — the largest collection of research datasets in the world.
The platform will power foundational models, automate scientific discovery, and speed up innovation across the nation’s most critical industries.
Genesis Mission brings together:
- U.S. national laboratories
- private-sector partners
- universities and research centers
- advanced manufacturing facilities
The focus spans energy, materials science, biotechnology, quantum technologies, and semiconductors.
A New National Science & Security Platform
The executive order also establishes the American Platform for Science and Security, the technical backbone of the mission, which will provide:
- high-performance computing resources, including DOE supercomputers
- secure cloud environments for training large AI models
- AI systems for simulations, optimization, and autonomous experimentation
- controlled access to federal, private, and open scientific datasets
- domain-specific foundational models for priority scientific fields
The Department of Energy (DOE) will lead the program, coordinate interagency efforts, and set unified security and data-sharing standards.
Strict Deadlines for Deployment
The directive outlines clear milestones:
- 60 days: identify at least 20 national scientific and technical challenges (quantum tech, critical materials, biotech, nuclear energy, manufacturing, semiconductors, etc.)
- 90 days: map all available compute and networking resources across federal partners and industry
- 120 days: select core datasets and models; develop a plan for integrating additional data sources
- 240 days: review robotic labs and AI-enabled manufacturing facilities capable of autonomous experimentation
- 270 days: demonstrate the platform’s initial operational capability for at least one selected national challenge
The mission will be coordinated by the Assistant to the President for Science and Technology through the National Science and Technology Council.
Additionally, plans include nationwide fellowship programs, internships, and placements in national laboratories to cultivate new scientific talent.
Broader Context
Trump has long signaled support for “industries of the future,” including AI and digital assets.
Shortly after taking office in January 2025, he introduced the Stargate Project, a massive AI-infrastructure initiative involving OpenAI, SoftBank, and Oracle, valued at up to $500 billion.
In mid-2025, the administration also moved toward securing $70 billion in private investments to scale U.S. AI and energy infrastructure.
